
NEWS
New publication on B cell maturation after SARS-CoV-2 mRNA vaccination
09 May 2022
The first data from the DigiHero is now officially published in Frontiers in Immunology.
We tracked B cells from individuals participating in the DigiHero study through their vaccination series including a third "booster" shot.
The percentage of antigen experienced SARS-CoV-2-specific B cells was low after the first two vaccinations but evolved over months and increased steeply after boosting. The third vaccination mobilized not only naïve, but also antigen-experienced B cell clones into further rapid somatic hypermutation trajectories indicating increased affinity.
These findings may explain why the third, but not the primary vaccination series, offers some protection against immune-escape variants such as Omicron
For more info on the DigiHero trial click here.
Welcome Denis!
01 April 2022

The Binderlab welcomes its newest member Denis Owczarek!
Denis has lots of academic and industry experience in antibody discovery and production.
We are really happy that he will help us to develop new CAR T cells.
Happy new year 2022
01 January 2022

The Binderlab wishes all of you and your friends and families a happy new year and a good start into 2022!
We have some big plans and are looking forward for the things to come.
Meanwhile, we celebrate this with a little gift to ourseleves and finally launch this website.